ZDHHC22

ZDHHC22 (Zinc Finger DHHC-Type Containing 22) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein-cysteine S-palmitoyltransferase activity.

Full Name

Zinc Finger DHHC-Type Containing 22

Function

Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (PubMed:22399288).
Catalyzes the palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (PubMed:22399288).
Might also mediate palmitoylation of CNN3 (By similarity).

Biological Process

Biological Process peptidyl-L-cysteine S-palmitoylation Source:GO_Central1 Publication
Biological Process protein localization to plasma membrane Source:UniProtKB1 Publication
Biological Process protein palmitoylation Source:UniProtKB1 Publication
Biological Process protein targeting to membrane Source:GO_Central1 Publication

Cellular Location

Endoplasmic reticulum membrane
Golgi apparatus membrane

Topology

Cytoplasmic: 1-9
Helical: 10-30
Lumenal: 31-48
Helical: 49-69
Cytoplasmic: 70-125
Helical: 126-167
Lumenal: 168-182
Helical: 183-203
Cytoplasmic: 204-263