ZFC3H1

Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor SKIV2L2/MTR4, which links to RNA-binding protein adapters.

Full Name

zinc finger, C3H1-type containing

Function

Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.

Biological Process

Biological Process RNA processing Source:InterPro

Cellular Location

Nucleus
Excluded from the nucleolus.

Anti-ZFC3H1 antibodies

Mouse Anti-ZFC3H1 Recombinant Antibody (CBYY-C1048) (CBMAB-C2485-YY)

Datasheet

SDS

Target: ZFC3H1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-C1048

Application*: E, IH, WB

Mouse Anti-ZFC3H1 Recombinant Antibody (3A3) (CBMAB-Z0197-WJ)

Datasheet

SDS

Target: ZFC3H1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3A3

Application*: E, P, WB

Mouse Anti-ZFC3H1 Recombinant Antibody (3A3) (CBMAB-C5641-LY)

Datasheet

SDS

Target: ZFC3H1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3A3

Application*: E, C, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)