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ZFC3H1

Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor SKIV2L2/MTR4, which links to RNA-binding protein adapters.

Full Name

zinc finger, C3H1-type containing

Function

Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.

Biological Process

Biological Process RNA processing Source:InterPro

Cellular Location

Nucleus
Excluded from the nucleolus.

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Anti-ZFC3H1 antibodies

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Mouse Anti-ZFC3H1 Recombinant Antibody (CBYY-C1048) (CBMAB-C2485-YY)

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Target: ZFC3H1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-C1048

Application*: E, IH, WB

Mouse Anti-ZFC3H1 Recombinant Antibody (3A3) (CBMAB-C5641-LY)

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Target: ZFC3H1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3A3

Application*: E, C, WB

Mouse Anti-ZFC3H1 Recombinant Antibody (3A3) (CBMAB-Z0197-WJ)

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Target: ZFC3H1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3A3

Application*: E, P, WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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