ACVR1B Matched Antibody Pair (018) (APMAB-018LY)

Name: ACVR1B Matched Antibody Pair (018)
SKU: APMAB-018LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-ACVR1B monoclonal, IgG2a antibody, 100 ug

Detection Antibody

Anti-ACVR1B Biotinylated mouse monoclonal, IgG1 antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Alternative Names

Activin A Receptor Type 1B; Serine/Threonine-Protein Kinase Receptor R2; Activin Receptor-Like Kinase 4; Activin A Receptor, Type IB; EC 2.7.11.30; ACVRLK4; ALK4; SKR2;

Entrez Gene ID

UniProt ID

P36896

More Infomation

References

Zheng, J., Zhang, T., Han, S., Liu, C., Liu, M., Li, S., & Li, J. (2021). Activin A improves the neurological outcome after ischemic stroke in mice by promoting oligodendroglial ACVR1B-mediated white matter remyelination. Experimental Neurology, 337, 113574.

Boueiz, A., Pham, B., Chase, R., Lamb, A., Lee, S., Naing, Z. Z. C., ... & Castaldi, P. J. (2019). Integrative genomics analysis identifies ACVR1B as a candidate causal gene of emphysema distribution. American journal of respiratory cell and molecular biology, 60(4), 388-398.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

ACVR1B Matched Antibody Pair (019)

Antibody Pairs

ACVR1B Matched Antibody Pair (019)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

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Second antibody and isotype control

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