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Mouse Anti-AATK Recombinant Antibody (V2-178873) (CBMAB-A0100-YC)

Provided herein is a Mouse monoclonal antibody against Human Apoptosis Associated Tyrosine Kinase. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all AATK antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-178873
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
AATK (AAH47378, 161-260 aa) partial recombinant protein with GST tag. Immunogen sequence: SPEFVLKEAQ EGCEPQAFAE LASEGEGPGP ETRLSTSLSG LNEKNPYRDS AYFSDLEAEA EATSGPEKKC GGDRAPGPEL GLRSTGQPSE QVCLRPGVSG
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 161-260

Target

Full Name
apoptosis-associated tyrosine kinase
Introduction
AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis o
Entrez Gene ID
9625
UniProt ID
Q6ZMQ8
Alternative Names
Apoptosis Associated Tyrosine Kinase; Lemur Tyrosine Kinase 1; Protein Phosphatase 1, Regulatory Subunit 77; Brain Apoptosis-Associated Tyrosine Kinase; CDK5-Binding Protein; P35-Binding Protein; EC 2.7.11.1; AATYK; LMTK1;
Function
May be involved in neuronal differentiation.
Biological Process
Brain development
Peptidyl-tyrosine autophosphorylation
Protein phosphorylation
Cellular Location
Cytoplasm; Membrane; Perinuclear region. Predominantly perinuclear.
PTM
Autophosphorylated. Phosphorylated by CDK5.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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