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Mouse Anti-AATK Recombinant Antibody (V2-178874) (CBMAB-A0101-YC)

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Datasheet
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
V2-178874
Application
FC
Immunogen
E. coli-derived recombinant human AATK (Asn421-Ala589)
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
FC0.25 µg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
apoptosis-associated tyrosine kinase
Introduction
AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis o
Entrez Gene ID
9625
UniProt ID
Q6ZMQ8
Alternative Names
Apoptosis Associated Tyrosine Kinase; Lemur Tyrosine Kinase 1; Protein Phosphatase 1, Regulatory Subunit 77; Brain Apoptosis-Associated Tyrosine Kinase; CDK5-Binding Protein; P35-Binding Protein; EC 2.7.11.1; AATYK; LMTK1;
Function
May be involved in neuronal differentiation.
Biological Process
Brain development
Peptidyl-tyrosine autophosphorylation
Protein phosphorylation
Cellular Location
Cytoplasm; Membrane; Perinuclear region. Predominantly perinuclear.
PTM
Autophosphorylated. Phosphorylated by CDK5.

Gao, L., Xia, T., Qin, M., Xue, X., Jiang, L., & Zhu, X. (2021). CircPTK2 Suppresses the Progression of Gastric Cancer by Targeting miR-196a-3p/AATK Axis.

Wang, K., Huang, R., Wu, C., Li, G., Zhao, Z., Hu, H., & Liu, Y. (2019). Receptor tyrosine kinase expression in high‑grade gliomas before and after chemoradiotherapy. Oncology letters, 18(6), 6509-6515.

Zhang, G., Zheng, H., Zhang, G., Cheng, R., Lu, C., Guo, Y., & Zhao, G. (2017). MicroRNA-338-3p suppresses cell proliferation and induces apoptosis of non-small-cell lung cancer by targeting sphingosine kinase 2. Cancer cell international, 17(1), 1-10.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-AATK Recombinant Antibody (V2-610868) (CAT#: CBMAB-A0011-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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