Rabbit Anti-ACY1 Recombinant Antibody (V2-179726) (CBMAB-A1086-YC)

Name: Rabbit Anti-ACY1 Recombinant Antibody (V2-179726)
SKU: CBMAB-A1086-YC
Rating: 5 (1 reviews)

See all ACY1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

V2-179726

Application

IHC-F, ICC, IF

Immunogen

Recombinant Human Aminoacylase-1 protein

Host Species

Rabbit

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
IF(ICC)	1:20-1:100
FC	1:25-1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Aminoacylase 1

Introduction

ACY1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is locat

Entrez Gene ID

UniProt ID

Q03154

Alternative Names

Aminoacylase 1; N-Acyl-L-Amino-Acid Amidohydrolase; EC 3.5.1.14; ACY-1; Epididymis Secretory Protein Li 5; Aminoacylase-1;

Function

Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).

Biological Process

Aflatoxin metabolic process
Cellular amino acid metabolic process

Cellular Location

Cytoplasm

Involvement in disease

Aminoacylase-1 deficiency (ACY1D): An enzymatic deficiency resulting in encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.

Chen, Z., Gao, J., Sun, J., Wu, Z., & Wang, B. (2021). Aminoacylase 1 (ACY-1) Mediates the Proliferation and Migration of Neuroblastoma Cells in Humans Through the ERK/Transforming Growth Factor β (TGF-β) Signaling Pathways. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 27, e928813-1.

Al-Helaly, L. A., & Mahmood, E. S. (2021). Biochemical and Histological Study of Aminoacylase-1 Purified from Amniotic Fluid in Rats with Oxidative Stress Induced by Lead Acetate. Baghdad Science Journal, 18(3), 0583-0583.

Xu, Z., Hu, Y., & Yu, Z. (2021). Effect of the ACY‑1 gene on HER2 and TRAIL expression in rectal carcinoma. Experimental and Therapeutic Medicine, 22(2), 1-7.

Wang, G., Li, H., & Hou, Y. (2021). LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma. Cancer Gene Therapy, 1-12.

Balamurugan, T. S. T., Huang, C. H., Chang, P. C., & Huang, S. T. (2018). Electrochemical molecular switch for the selective profiling of cysteine in live cells and whole blood and for the quantification of aminoacylase-1. Analytical chemistry, 90(21), 12631-12638.

Cheng, Q., Gu, S., Liu, Z., Wang, C. Z., & Li, X. (2017). Expressional divergence of the fatty acid-amino acid conjugate-hydrolyzing aminoacylase 1 (L-ACY-1) in Helicoverpa armigera and Helicoverpa assulta. Scientific reports, 7(1), 1-11.

Yu, B., Liu, X., Cao, X., Zhang, M., & Chang, H. (2017). Study of the expression and function of ACY1 in patients with colorectal cancer. Oncology letters, 13(4), 2459-2464.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-ACY1 Recombinant Antibody (V2-179726)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

ACY1 Matched Antibody Pair (020) (CAT#: APMAB-020LY)

ACY1 Matched Antibody Pair (021) (CAT#: APMAB-021LY)

ACY1 Matched Antibody Pair (022) (CAT#: APMAB-022LY)

Related Products

ACY1 Matched Antibody Pair (021) (CAT#: APMAB-021LY)

Rat Anti-ACY1 Recombinant Antibody (V2-179722) (CAT#: CBMAB-A1082-YC)

Mouse Anti-ACY1 Recombinant Antibody (V2-179725) (CAT#: CBMAB-A1085-YC)

ACY1 Matched Antibody Pair (022) (CAT#: APMAB-022LY)

Mouse Anti-ACY1 Recombinant Antibody (V2-179719) (CAT#: CBMAB-A1079-YC)

Rabbit Anti-ACY1 Recombinant Antibody (V2-179707) (CAT#: CBMAB-A1067-YC)

Mouse Anti-ACY1 Recombinant Antibody (V2-179708) (CAT#: CBMAB-A1068-YC)

Mouse Anti-ACY1 Recombinant Antibody (V2-179710) (CAT#: CBMAB-A1070-YC)

Mouse Anti-ACY1 Recombinant Antibody (V2-179721) (CAT#: CBMAB-A1081-YC)

Mouse Anti-ACY1 Recombinant Antibody (V2-179714) (CAT#: CBMAB-A1074-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry