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Mouse Anti-ADH4 Recombinant Antibody (V2-179898) (CBMAB-A1282-YC)

Provided herein is a Mouse monoclonal antibody against Human Alcohol Dehydrogenase 4 (Class II), Pi Polypeptide. The antibody can be used for immunoassay techniques, such as ELISA, RNAi, WB.
See all ADH4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-179898
Antibody Isotype
IgG1, κ
Application
ELISA, RNAi, WB

Basic Information

Immunogen
ADH4 (NP_000661, 52-150 aa) partial recombinant protein with GST tag. Immunogen sequence: SVIDSKFEGL AFPVIVGHEA AGIVESIGPG VTNVKPGDKV IPLYAPLCRK CKFCLSPLTN LCGKISNLKS PASDQQLMED KTSRFTCKGK PVYHFFGTS
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 52-150

Target

Full Name
alcohol dehydrogenase 4 (class II), pi polypeptide
Introduction
ADH4 is class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and l
Entrez Gene ID
127
UniProt ID
P08319
Alternative Names
Alcohol Dehydrogenase 4 (Class II), Pi Polypeptide; Alcohol Dehydrogenase Class II Pi Chain; EC 1.1.1.1; Epididymis Secretory Protein Li 4; Alcohol Dehydrogenase 4; Aldehyde Reductase; EC 1.1.1; HEL-S-4; ADH-2;
Function
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones.
Biological Process
Alcohol catabolic process
Alcohol metabolic process
Cellular aldehyde metabolic process
Ethanol oxidation
Fatty acid omega-oxidation
Formaldehyde catabolic process
Quinone metabolic process
Retinoid metabolic process
Retinol metabolic process
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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