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ADH4

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq]
Full Name
alcohol dehydrogenase 4 (class II), pi polypeptide
Function
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones.
Biological Process
Alcohol catabolic process
Alcohol metabolic process
Cellular aldehyde metabolic process
Ethanol oxidation
Fatty acid omega-oxidation
Formaldehyde catabolic process
Quinone metabolic process
Retinoid metabolic process
Retinol metabolic process
Cellular Location
Cytoplasm
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Anti-ADH4 antibodies

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Mouse Anti-ADH4 Recombinant Antibody (V2-179899) (CBMAB-A1283-YC)

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Target: ADH4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-179899
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ADH4 Recombinant Antibody (V2-179898) (CBMAB-A1282-YC)

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Target: ADH4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-179898
Application*: E, RNAi, WB
Datasheet SDS

Mouse Anti-ADH4 Recombinant Antibody (V2-179897) (CBMAB-A1281-YC)

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Target: ADH4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179897
Application*: E, IH, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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