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Mouse Anti-ALDH7A1 Recombinant Antibody (CBYC-A526) (CBMAB-A2307-YC)

Provided herein is a Mouse monoclonal antibody against Human Aldehyde Dehydrogenase 7 Family Member A1. The antibody can be used for immunoassay techniques, such as ELISA, ICC, WB.
See all ALDH7A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Avian
Clone
CBYC-A526
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Recombinant Human ALDH7A1 protein
Host Species
Mouse
Specificity
Human, Avian
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-539

Target

Full Name
Aldehyde Dehydrogenase 7 Family Member A1
Introduction
ALDH7A1 is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to
Entrez Gene ID
501
UniProt ID
P49419
Alternative Names
Aldehyde Dehydrogenase 7 Family Member A1; Alpha-AASA Dehydrogenase; P6c Dehydrogenase; Delta1-Piperideine-6-Carboxylate Dehydrogenase; Alpha-Aminoadipic Semialdehyde Dehydrogenase; Betaine Aldehyde Dehydrogenase; 26g Turgor Protein Homolog; Antiquitin-1;
Function
Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.
Biological Process
Cellular aldehyde metabolic process Source: UniProtKB
Choline catabolic process Source: Reactome
Glycine betaine biosynthetic process from choline Source: UniProtKB-UniPathway
Lysine catabolic process Source: Reactome
Sensory perception of sound Source: ProtInc
Cellular Location
Nucleus; Cytosol
Isoform 1: Mitochondrion
Involvement in disease
Pyridoxine-dependent epilepsy (PDE): Characterized by a combination of various seizure types. It usually occurs in the first hours of life and is unresponsive to standard anticonvulsants, responding only to immediate administration of pyridoxine hydrochloride.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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