Mouse Anti-ART1 Recombinant Antibody (6E2) (CBMAB-A3682-YC)

Provided herein is a Mouse monoclonal antibody against Human ADP-Ribosyltransferase 1. The antibody can be used for immunoassay techniques, such as WB.
See all ART1 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

6E2

Antibody Isotype

IgG2b

Application

Basic Information

Immunogen

Human recombinant protein fragment corresponding to amino acids 83-295 of human ART1 (NP_004305) produced in E. coli.

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

ADP-Ribosyltransferase 1

Introduction

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-l

Entrez Gene ID

417

UniProt ID

P52961

Alternative Names

ADP-Ribosyltransferase 1; ADP-Ribosyltransferase C2 And C3 Toxin-Like 1; Mono(ADP-Ribosyl)Transferase 1; ARTC1; GPI-Linked NAD(P)(+)--Arginine ADP-Ribosyltransferase 1; ADP-Ribosyltransferase 2;

Function

Has ADP-ribosyltransferase activity toward GLP1R.

Biological Process

Peptidyl-arginine ADP-ribosylation Source: GO_Central
Protein ADP-ribosylation Source: ProtInc

Cellular Location

Sarcoplasmic reticulum membrane

References

Mukherjee, S., Wennerberg, E., Hung, C., Saadallah, N., Kariyawasam, S., Hussein, M. K., ... & Stiles, B. M. (2020). A05 ART1, a Mono-ADP-Ribosyltransferase, Regulates Tumor-Infiltrating CD8+ T Cells and Is Highly Expressed in EGFR Mutated Lung Cancers. Journal of Thoracic Oncology, 15(2), S13.

Mukherjee, S., Wennerberg, E., Hung, C., Saadallah, N., Kariyawasam, S., Agrusa, C., ... & Stiles, B. (2020). Art1, an extracellular mono-ADP-ribosyltransferase, is upregulated in response to cellular stress and promotes lung cancer growth.

Chen, W., Yang, Y., Duan, J., Li, M., Tang, Y., Zhang, S., ... & Wang, Y. (2020). High Norepinephrine Status Induced Growth of Colorectal Cancer With Type 2 Diabetes Mellitus Benefited From ADP-Ribosyltransferase 1.

Zhou, L., Zhan, M. L., Tang, Y., Xiao, M., Li, M., Li, Q. S., ... & Wang, Y. L. (2018). Effects of β-caryophyllene on arginine ADP-ribosyltransferase 1-mediated regulation of glycolysis in colorectal cancer under high-glucose conditions. International journal of oncology, 53(4), 1613-1624.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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