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Mouse Anti-ASNS Recombinant Antibody (1A10) (CBMAB-A3794-YC)

Provided herein is a Mouse monoclonal antibody against Human Asparagine Synthetase (Glutamine-Hydrolyzing). The antibody can be used for immunoassay techniques, such as IF, WB.
See all ASNS antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
1A10
Antibody Isotype
IgG2b
Application
IF, WB

Basic Information

Immunogen
Full length human recombinant protein of human ASNS(NP_597680) produced in HEK293T cell.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000
IF(ICC)1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
asparagine synthetase
Introduction
ASNS is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature.
Entrez Gene ID
440
UniProt ID
P08243
Alternative Names
Asparagine Synthetase (Glutamine-Hydrolyzing); Glutamine-Dependent Asparagine Synthetase; EC 6.3.5.4; TS11; Asparagine Synthetase [Glutamine-Hydrolyzing]; TS11 Cell Cycle Control Protein; Cell Cycle Control Protein TS11; Asparagine Synthetase; ASNSD;
Biological Process
Asparagine biosynthetic process Source: MGI
Aspartate family amino acid metabolic process Source: Reactome
Cellular response to glucose starvation Source: UniProtKB
Cellular response to hormone stimulus Source: Ensembl
Glutamine metabolic process Source: UniProtKB-KW
L-asparagine biosynthetic process Source: UniProtKB-UniPathway
Liver development Source: Ensembl
Negative regulation of apoptotic process Source: UniProtKB
Positive regulation of mitotic cell cycle Source: UniProtKB
Response to amino acid Source: Ensembl
Response to follicle-stimulating hormone Source: Ensembl
Response to light stimulus Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to methotrexate Source: Ensembl
Response to toxic substance Source: Ensembl
Cellular Location
Cytosol
Involvement in disease
Asparagine synthetase deficiency (ASNSD): An inborn error of asparagine biosynthesis that results in a severe neurologic disorder characterized by microcephaly, severely delayed psychomotor development, progressive encephalopathy, cortical atrophy, and seizure or hyperekplexic activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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