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Mouse Anti-ASNS Recombinant Antibody (2B3) (CBMAB-A0545-LY)

The product is antibody recognizes ASNS. The antibody 2B3 immunoassay techniques such as: sELISA, ELISA.
See all ASNS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2B3
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
ASNS (AAH14621, 281 a.a. ~ 380 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
asparagine synthetase
Introduction
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. There are three alternatively spliced transcript variants encoding the same protein described for this gene. [provided by RefSeq]
Entrez Gene ID
440
UniProt ID
P08243
Alternative Names
TS11
Biological Process
Asparagine biosynthetic process Source: MGI
Aspartate family amino acid metabolic process Source: Reactome
Cellular response to glucose starvation Source: UniProtKB
Cellular response to hormone stimulus Source: Ensembl
Glutamine metabolic process Source: UniProtKB-KW
L-asparagine biosynthetic process Source: UniProtKB-UniPathway
Liver development Source: Ensembl
Negative regulation of apoptotic process Source: UniProtKB
Positive regulation of mitotic cell cycle Source: UniProtKB
Response to amino acid Source: Ensembl
Response to follicle-stimulating hormone Source: Ensembl
Response to light stimulus Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to methotrexate Source: Ensembl
Response to toxic substance Source: Ensembl
Cellular Location
Cytosol
Involvement in disease
Asparagine synthetase deficiency (ASNSD): An inborn error of asparagine biosynthesis that results in a severe neurologic disorder characterized by microcephaly, severely delayed psychomotor development, progressive encephalopathy, cortical atrophy, and seizure or hyperekplexic activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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