Mouse Anti-ATG10 Recombinant Antibody (CBT4019) (V2LY-0625-LY1312)

Go to compare Compare Online Inquiry
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBT4019
Application
WB
Immunogen
Purified recombinant fragment of human ATG10 (AA: 1-125) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Autophagy Related 10
Entrez Gene ID
UniProt ID
Function
E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity).
Plays a role in adenovirus-mediated cell lysis.
Biological Process
Autophagy Source: UniProtKB
ER overload response Source: BHF-UCL
Macroautophagy Source: GO_Central
Positive regulation of protein modification process Source: UniProtKB
Protein lipidation Source: UniProtKB
Protein modification by small protein conjugation Source: UniProtKB
Protein transport Source: UniProtKB-KW
Cellular Location
Cytoplasm

Abbasi Teshnizi, F., Kazemipour, N., Nazifi, S., Bagheri Lankarani, K., Sepehrimanesh, M., & Razeghian Jahromi, I. (2021). A study on the potential role of autophagy‐related protein 10 as a biomarker for ulcerative colitis. Physiological Reports, 9(7), e14825.

Shen, H., Lin, Z., Shi, H., Wu, L., Ma, B., Li, H., ... & Yin, X. (2020). MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma. 3 Biotech, 10(8), 1-11.

Han, Z., Wang, W., Lv, X., Zong, Y., Liu, S., Liu, Z., ... & Song, L. (2019). ATG10 (autophagy-related 10) regulates the formation of autophagosome in the anti-virus immune response of pacific oyster (Crassostrea gigas). Fish & shellfish immunology, 91, 325-332.

Catanese, A., Olde Heuvel, F., Mulaw, M., Demestre, M., Higelin, J., Barbi, G., ... & Boeckers, T. M. (2019). Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation. Autophagy, 15(10), 1719-1737.

Zhang, M. Q., Li, J. R., Peng, Z. G., & Zhang, J. P. (2018). Differential effects of autophagy-related 10 protein on HCV replication and autophagy flux are mediated by its cysteine44 and cysteine135. Frontiers in immunology, 9, 2176.

Nooraei, M. S., Noori-Zadeh, A., Darabi, S., Rajaei, F., Golmohammadi, Z., & Abbaszadeh, H. A. (2018). Low level of autophagy-related gene 10 (ATG10) expression in the 6-hydroxydopamine rat model of Parkinson’s disease. Iranian biomedical journal, 22(1), 15.

Zhao, Q., Hu, Z. Y., Zhang, J. P., Jiang, J. D., Ma, Y. Y., Li, J. R., ... & Chen, J. H. (2017). Dual roles of two isoforms of autophagy-related gene ATG10 in HCV-subgenomic replicon mediated autophagy flux and innate immunity. Scientific reports, 7(1), 1-15.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-ATG10 Recombinant Antibody (CBT4019)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry