ATG10

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
Full Name
Autophagy Related 10
Function
E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity).
Plays a role in adenovirus-mediated cell lysis.
Biological Process
Autophagy Source: UniProtKB
ER overload response Source: BHF-UCL
Macroautophagy Source: GO_Central
Positive regulation of protein modification process Source: UniProtKB
Protein lipidation Source: UniProtKB
Protein modification by small protein conjugation Source: UniProtKB
Protein transport Source: UniProtKB-KW
Cellular Location
Cytoplasm
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Anti-ATG10 antibodies

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Mouse Anti-ATG10 Recombinant Antibody (5A7) (CBMAB-A3889-YC)

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Target: ATG10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5A7
Application*: WB
Datasheet SDS

Rabbit Anti-ATG10 Recombinant Antibody (SR1389) (CBMAB-1157-CN)

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Target: ATG10
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SR1389
Application*: WB, IP
Datasheet SDS

Mouse Anti-ATG10 Recombinant Antibody (CBT4019) (V2LY-0625-LY1312)

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Target: ATG10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4019
Application*: WB
Datasheet SDS

Mouse Anti-ATG10 Recombinant Antibody (CBT2545) (V2LY-0625-LY1311)

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Target: ATG10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2545
Application*: WB, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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