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Mouse Anti-BCAN Recombinant Antibody (450616) (CBMAB-1193-CN)

This product is a mouse antibody that recognizes BCAN of human. The antibody 450616 can be used for immunoassay techniques such as: ICC.
See all BCAN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
450616
Antibody Isotype
IgG1
Application
ICC

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Brevican isoform 1.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IF(ICC)8-25 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Brevican
Introduction
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. The protein may play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Entrez Gene ID
63827
UniProt ID
Q96GW7
Alternative Names
BEHAB; CSPG7
Function
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Biological Process
Cell adhesion Source: InterPro
Central nervous system development Source: GO_Central
Chondroitin sulfate biosynthetic process Source: Reactome
Chondroitin sulfate catabolic process Source: Reactome
Dermatan sulfate biosynthetic process Source: Reactome
Extracellular matrix organization Source: Reactome
Hippocampus development Source: Ensembl
Skeletal system development Source: GO_Central
Synapse maturation Source: Ensembl
Cellular Location
Isoform 1: Extracellular matrix
Isoform 2: Membrane
PTM
Contains mostly chondroitin sulfate (By similarity). O-glycosylated with a core 1 or possibly core 8 glycan.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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