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Mouse Anti-BCAN Recombinant Antibody (S294A-6) (CBMAB-1194-CN)

This product is a mouse antibody that recognizes BCAN of rat. The antibody S294A-6 can be used for immunoassay techniques such as: WB, IF.
See all BCAN antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
S294A-6
Antibody Isotype
IgG2b
Application
WB, IF

Basic Information

Immunogen
Fusion protein amino acids 219-655 of rat Brevican.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH7.4, 50% glycerol
Preservative
0.09% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Brevican
Introduction
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. The protein may play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Entrez Gene ID
25393
UniProt ID
P55068
Alternative Names
BEHAB; ALPBRE
Function
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Biological Process
Cell adhesion Source: InterPro
Central nervous system development Source: GO_Central
Chondroitin sulfate biosynthetic process Source: Reactome
Chondroitin sulfate catabolic process Source: Reactome
Dermatan sulfate biosynthetic process Source: Reactome
Extracellular matrix organization Source: Reactome
Hippocampus development Source: Ensembl
Skeletal system development Source: GO_Central
Synapse maturation Source: Ensembl
Cellular Location
Isoform 1: Extracellular matrix
Isoform 2: Membrane
PTM
Contains mostly chondroitin sulfate (By similarity). O-glycosylated with a core 1 or possibly core 8 glycan.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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