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Mouse Anti-BEX3 Recombinant Antibody (4E5) (CBMAB-N0634-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4E5
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
NGFRAP1 (AAH03190, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Brain Expressed X-Linked 3
Introduction
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Entrez Gene ID
27018
UniProt ID
Q00994
Alternative Names
Brain Expressed X-Linked 3; Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1; Ovarian Granulosa Cell 13.0 KDa Protein HGR74; P75NTR-Associated Cell Death Executor; Brain-Expressed X-Linked Protein 3; DXS6984E; NGFRAP1;
Function
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity).
May play an important role in the pathogenesis of neurogenetic diseases.
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Apoptotic process Source: UniProtKB-KW
Multicellular organism development Source: ProtInc
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Signal transduction Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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