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Mouse Anti-BEX3 Recombinant Antibody (CBWJN-1053) (CBMAB-N0636-WJ)

This product is a Mouse antibody that recognizes BEX3. The antibody CBWJN-1053 can be used for immunoassay techniques such as: WB, IHC-P, ICC.
See all BEX3 antibodies
Published Data
Mouse Anti-BEX3 Recombinant Antibody (CBWJN-1053) (CBMAB-N0636-WJ) in ICC
ICC analysis of protein expression level of BEX3 in NPC cells exposed to cisplatin. Blue-fluorescent DAPI was used to stain the nucleus. ...View More
Zarei, M., Acharya, P., & Talahalli, R. R. (2021). Ginger and turmeric lipid-solubles attenuate heated oil-induced hepatic inflammation via the downregulation of NF-kB in rats. Life Sciences, 265, 118856.
Mouse Anti-BEX3 Recombinant Antibody (CBWJN-1053) (CBMAB-N0636-WJ) in ICC
ICC analysis of mRNA and protein expression level of BEX3, OCT4 and CD271 in parental and cisplatin-resistant HONE1. ...View More
Zarei, M., Acharya, P., & Talahalli, R. R. (2021). Ginger and turmeric lipid-solubles attenuate heated oil-induced hepatic inflammation via the downregulation of NF-kB in rats. Life Sciences, 265, 118856.
Mouse Anti-BEX3 Recombinant Antibody (CBWJN-1053) (CBMAB-N0636-WJ) in ICC
ICC analysis of protein and mRNA expression level of BEX3 in HONE1 and HK1 cells transfected with BEX3 siRNA. ...View More
Zarei, M., Acharya, P., & Talahalli, R. R. (2021). Ginger and turmeric lipid-solubles attenuate heated oil-induced hepatic inflammation via the downregulation of NF-kB in rats. Life Sciences, 265, 118856.
Mouse Anti-BEX3 Recombinant Antibody (CBWJN-1053) (CBMAB-N0636-WJ) in IHC
IHC analysis of protein expression level of BEX3 in xenograft derived from parental HONE1 or cisplatin-resistant HONE1 under cisplatin treatment. Scale bar = 50 μm. ...View More
Zarei, M., Acharya, P., & Talahalli, R. R. (2021). Ginger and turmeric lipid-solubles attenuate heated oil-induced hepatic inflammation via the downregulation of NF-kB in rats. Life Sciences, 265, 118856.

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBWJN-1053
Antibody Isotype
IgG2b
Application
WB, IHC

Basic Information

Immunogen
E. coli-derived recombinant human NGFRAP1/BEX3 Met1-Pro111.
Host Species
Mouse
Specificity
Human, Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1-2 μg/ml
IHC8-25 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Brain Expressed X-Linked 3
Introduction
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Entrez Gene ID
27018
UniProt ID
Q00994
Alternative Names
Brain Expressed X-Linked 3; Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1; Ovarian Granulosa Cell 13.0 KDa Protein HGR74; P75NTR-Associated Cell Death Executor; Brain-Expressed X-Linked Protein 3; DXS6984E; NGFRAP1;
Function
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity).
May play an important role in the pathogenesis of neurogenetic diseases.
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Apoptotic process Source: UniProtKB-KW
Multicellular organism development Source: ProtInc
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Signal transduction Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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