BEX3
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Full Name
Brain Expressed X-Linked 3
Function
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity).
May play an important role in the pathogenesis of neurogenetic diseases.
May play an important role in the pathogenesis of neurogenetic diseases.
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Apoptotic process Source: UniProtKB-KW
Multicellular organism development Source: ProtInc
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Signal transduction Source: GO_Central
Apoptotic process Source: UniProtKB-KW
Multicellular organism development Source: ProtInc
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
Signal transduction Source: GO_Central
Cellular Location
Cytoplasm; Nucleus. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
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Anti-BEX3 antibodies
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Target: BEX3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4E5
Application*: E, WB
Target: BEX3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBWJN-1053
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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