Mouse Anti-BIN3 Recombinant Antibody (CBYY-0597) (CBMAB-0600-YY)

Name: Mouse Anti-BIN3 Recombinant Antibody (CBYY-0597)
SKU: CBMAB-0600-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYY-0597

Application

WB, IF, FC

Immunogen

Full length human recombinant protein of human BIN3 produced in HEK293T cell.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:500
IF(ICC)	1:100
FC	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

Batch dependent

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

bridging integrator 3

Introduction

The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.

Entrez Gene ID

Human	55909
Dog	608969
Monkey	708840

UniProt ID

Human	Q9NQY0
Dog	F1PTG7
Monkey	G8F4G3

Alternative Names

Bridging Integrator 3;

Function

Involved in cytokinesis and septation where it has a role in the localization of F-actin.

Biological Process

Actin cortical patch localization Source: GO_Central
Actin filament organization Source: UniProtKB
Cytoskeleton-dependent cytokinesis Source: UniProtKB
Division septum assembly Source: UniProtKB-KW
Endocytosis Source: GO_Central
Myoblast migration involved in skeletal muscle regeneration Source: Ensembl
Plasma membrane tubulation Source: GO_Central
Protein localization Source: UniProtKB
Regulation of lamellipodium assembly Source: Ensembl
Skeletal muscle fiber development Source: Ensembl
Unidimensional cell growth Source: UniProtKB

Cellular Location

Cytoskeleton

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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