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Mouse Anti-BIN3 Recombinant Antibody (CBYY-0597) (CBMAB-0600-YY)

This product is mouse antibody that recognizes BIN3. The antibody CBYY-0597 can be used for immunoassay techniques such as: WB, IHC, IF, FC
See all BIN3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-0597
Antibody Isotype
IgG1
Application
WB, IF, FC

Basic Information

Immunogen
Full length human recombinant protein of human BIN3 produced in HEK293T cell.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500
IF(ICC)1:100
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
bridging integrator 3
Introduction
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
Entrez Gene ID
Human55909
Dog608969
Monkey708840
UniProt ID
HumanQ9NQY0
DogF1PTG7
MonkeyG8F4G3
Alternative Names
Bridging Integrator 3;
Function
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Biological Process
Actin cortical patch localization Source: GO_Central
Actin filament organization Source: UniProtKB
Cytoskeleton-dependent cytokinesis Source: UniProtKB
Division septum assembly Source: UniProtKB-KW
Endocytosis Source: GO_Central
Myoblast migration involved in skeletal muscle regeneration Source: Ensembl
Plasma membrane tubulation Source: GO_Central
Protein localization Source: UniProtKB
Regulation of lamellipodium assembly Source: Ensembl
Skeletal muscle fiber development Source: Ensembl
Unidimensional cell growth Source: UniProtKB
Cellular Location
Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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