BIN3
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq]
Full Name
bridging integrator 3
Function
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Biological Process
Actin cortical patch localization Source: GO_Central
Actin filament organization Source: UniProtKB
Cytoskeleton-dependent cytokinesis Source: UniProtKB
Division septum assembly Source: UniProtKB-KW
Endocytosis Source: GO_Central
Myoblast migration involved in skeletal muscle regeneration Source: Ensembl
Plasma membrane tubulation Source: GO_Central
Protein localization Source: UniProtKB
Regulation of lamellipodium assembly Source: Ensembl
Skeletal muscle fiber development Source: Ensembl
Unidimensional cell growth Source: UniProtKB
Actin filament organization Source: UniProtKB
Cytoskeleton-dependent cytokinesis Source: UniProtKB
Division septum assembly Source: UniProtKB-KW
Endocytosis Source: GO_Central
Myoblast migration involved in skeletal muscle regeneration Source: Ensembl
Plasma membrane tubulation Source: GO_Central
Protein localization Source: UniProtKB
Regulation of lamellipodium assembly Source: Ensembl
Skeletal muscle fiber development Source: Ensembl
Unidimensional cell growth Source: UniProtKB
Cellular Location
Cytoskeleton
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Anti-BIN3 antibodies
+ Filters

Target: BIN3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-2078
Application*: WB, E
Target: BIN3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-2021
Application*: WB
Target: BIN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-1992
Application*: FC, WB
Target: BIN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-0597
Application*: WB, IF, FC
Target: BIN3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-0592
Application*: IP, E, WB, IF
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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