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Mouse Anti-BRK1 Recombinant Antibody (CBLC009-LY) (CBMAB-C9495-LY)

The product is antibody recognizes BRK1. The antibody CBLC009-LY immunoassay techniques such as: ELISA, IHC-P, WB.
See all BRK1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLC009-LY
Antibody Isotype
IgG2b
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.02% Proclin300
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
BRICK1, SCAR/WAVE Actin Nucleating Complex Subunit
Introduction
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Entrez Gene ID
55845
UniProt ID
Q8WUW1
Alternative Names
BRICK1, SCAR/WAVE Actin Nucleating Complex Subunit; Haematopoietic Stem/Progenitor Cell Protein 300; C3orf10; BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit, Homolog (Arabidopsis Thaliana); BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit; Chromosome 3 Open Reading Frame 10;
Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Biological Process
Actin filament organization Source: InterPro
Cell motility Source: GO_Central
Fc-gamma receptor signaling pathway involved in phagocytosis Source: Reactome
In utero embryonic development Source: Ensembl
Positive regulation of Arp2/3 complex-mediated actin nucleation Source: UniProtKB
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of lamellipodium assembly Source: ARUK-UCL
Positive regulation of protein-containing complex assembly Source: UniProtKB
Rac protein signal transduction Source: UniProtKB
Regulation of actin polymerization or depolymerization Source: GO_Central
Vascular endothelial growth factor receptor signaling pathway Source: Reactome
Cellular Location
Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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