BRK1

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Full Name
BRICK1, SCAR/WAVE Actin Nucleating Complex Subunit
Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Biological Process
Actin filament organization Source: InterPro
Cell motility Source: GO_Central
Fc-gamma receptor signaling pathway involved in phagocytosis Source: Reactome
In utero embryonic development Source: Ensembl
Positive regulation of Arp2/3 complex-mediated actin nucleation Source: UniProtKB
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of lamellipodium assembly Source: ARUK-UCL
Positive regulation of protein-containing complex assembly Source: UniProtKB
Rac protein signal transduction Source: UniProtKB
Regulation of actin polymerization or depolymerization Source: GO_Central
Vascular endothelial growth factor receptor signaling pathway Source: Reactome
Cellular Location
Cytoskeleton
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Anti-BRK1 antibodies

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Mouse Anti-BRK1 Recombinant Antibody (CBLC009-LY) (CBMAB-C9495-LY)

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Target: BRK1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLC009-LY
Application*: E, WB
Datasheet SDS

Mouse Anti-BRK1 Recombinant Antibody (CBYC-P030) (CBMAB-P0117-YC)

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Target: BRK1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYC-P030
Application*: E, WB
Datasheet SDS

Mouse Anti-BRK1 Recombinant Antibody (CBYY-C0776) (CBMAB-C2212-YY)

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Target: BRK1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C0776
Application*: WB, IP, IF, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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