Mouse Anti-BTBD1 Recombinant Antibody (CBYY-1808) (CBMAB-2157-YY)

Name: Mouse Anti-BTBD1 Recombinant Antibody (CBYY-1808)
SKU: CBMAB-2157-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-1808

Application

WB, IP, IF, E

Immunogen

Amino acids 1-60 mapping at the N-terminus of BTBD1 of human origin.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

0.09% sodium azide

Concentration

0.2 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

BTB (POZ) domain containing 1

Introduction

The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), Bovineth of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic Bovinedies. Alternative splicing results in multiple transcript variants encoding different isoforMouse.

Entrez Gene ID

53339

UniProt ID

Q9H0C5

Alternative Names

BTB Domain Containing 1; Hepatitis C Virus NS5A-Transactivated Protein 8; HCV NS5A-Transactivated Protein 8; BTB (POZ) Domain Containing 1; C15orf1; NS5ATP8; BTB/POZ Domain-Containing Protein 1;

Function

Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312).
Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism (By similarity).
May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis (By similarity).

Biological Process

Muscle organ development Source: UniProtKB-KW
Neurogenesis Source: GO_Central
Post-translational protein modification Source: Reactome
Protein ubiquitination Source: UniProtKB-UniPathway
Regulation of protein binding Source: UniProtKB

Cellular Location

Cytoplasm. Localizes to punctate or elongated cytoplasmic bodies.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-BTBD1 Recombinant Antibody (3E11) (CAT#: CBMAB-A0894-LY)

Isotype control

For research use only. Not intended for any clinical use.

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