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Creative Biolabs has successfully developed SARS, MERS and other anti-viral antibodies in the past to assist scientific research. Facing the difficult COVID-19, Creative Biolabs actively invests in antibody development to assist researchers to better understand the characteristics of 2019-nCoV and drug development. Currently, Creative Biolabs is proud to offer an extensive line of research antibodies to support the study of SARS-CoV-2/COVID-19, several of which were validated using virus-infected cell lysates.

Explore the collections of SARS-CoV-2/COVID-19 antibodies >

Mouse Anti-BTRC Recombinant Antibody (CBYY-0931) (CBMAB-0934-YY)

This product is mouse antibody that recognizes BTRC. The antibody CBYY-0931 can be used for immunoassay techniques such as: WB, IF
Host Species
Mouse
Application
WB, IF
Immunogen
Human fragment corresponding to amino acids 52-354 of human BTRC (NP_378663) produced in E.coli
Antibody Isotype
IgG1
Specificity
Human
Clone
CBYY-0931
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes a member of the F-Bovinex protein family which is characterized by an approximately 40 amino acid motif, the F-Bovinex. The F-Bovinex proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-Bovinex), which function in phosphorylation-dependent ubiquitination. The F-Bovinex proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-Bovinex, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012]
Alternative Name
Beta-Transducin Repeat Containing E3 Ubiquitin Protein Ligase; F-Bovinex And WD Repeats Protein Beta-TrCP; PIkappaBalpha-E3 Receptor Subunit; Epididymis Tissue Protein Li 2a; E3RSIkappaB; FBXW1A; BTrCP; FBW1A; F-Bovinex/WD Repeat-Containing Protein 1A;
Entrez Gene ID
UniProt ID
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Please try the standard protocols which include: protocols, troubleshooting and guide.

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Cat CBMAB-0934-YY
Conjugates
Size
Price $
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Second antibody and isotype control