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Mouse Anti-C1GALT1 Recombinant Antibody (1F1) (CBMAB-C3996-LY)

This product is antibody recognizes C1GALT1. The antibody 1F1 immunoassay techniques such as: ELISA, WB.
See all C1GALT1 antibodies
Published Data
Fig.1 Western blot analyses showing C1GALT1 expression in paired hepatocellular carcinoma tissues from A. Representative images are shown. N, nontumor liver tissue; T, tumor tissue.
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Fig.2 Immunohistochemistry of C1GALT1 in paired primary hepatocellular carcinoma tissues. The brown stained cells in the tumor part are hepatocellular carcinoma cells, and those in the nontumor part are hepatocytes.
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Fig.3 Expression of C1GALT1 in hepatocellular carcinoma cell lines.
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Fig.4 Effects of C1GALT1 on binding of VVA to glycoproteins.
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Fig.5 C1GALT1 regulates activity of MET in hepatocellular carcinoma cells.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F1
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.26 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
Entrez Gene ID
56913
UniProt ID
Q9NS00
Function
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Biological Process
Angiogenesis Source: UniProtKB
Cell differentiation Source: UniProtKB-KW
Kidney development Source: UniProtKB
O-glycan processing Source: Reactome
O-glycan processing, core 1 Source: GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-6 aa
Helical: 7-29 aa
Lumenal: 30-363 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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