Rat Anti-CA1 Recombinant Antibody (CBXC-1142) (CBMAB-C1408-CQ)

Name: Rat Anti-CA1 Recombinant Antibody (CBXC-1142)
SKU: CBMAB-C1408-CQ
Rating: 5 (1 reviews)

See all CA1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

CBXC-1142

Application

Immunogen

E. coli-derived recombinant human Carbonic Anhydrase I/CA1 Ala2-Phe261.

Host Species

Rat

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	0.5 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Preservative

None

Concentration

LYOPH

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

carbonic anhydrase 1

Introduction

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

759

UniProt ID

P00915

Alternative Names

CA-I; CAB; Car1; HEL-S-11

Function

Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.

Biological Process

Bicarbonate transport Source: Reactome
Interleukin-12-mediated signaling pathway Source: Reactome
One-carbon metabolic process Source: GO_Central

Cellular Location

Cytoplasm

Feng, Y., Zhong, M., Tang, Y., Liu, X., Liu, Y., Wang, L., & Zhou, H. (2020). The role and underlying mechanism of exosomal CA1 in chemotherapy resistance in diffuse large B cell lymphoma. Molecular Therapy-Nucleic Acids, 21, 452-463.

Yuan, L., Wang, M., Liu, T., Lei, Y., Miao, Q., Li, Q., ... & Chang, X. (2019). Carbonic anhydrase 1-mediated calcification is associated with atherosclerosis, and methazolamide alleviates its pathogenesis. Frontiers in pharmacology, 10, 766.

Lu, D., Peng, X., Jia, X., Li, G., Tan, N., Wei, Z., ... & Liu, J. (2019). Carbonic Anhydrase I modifies SOD1-induced motor neuron toxicity in< em> Drosophila via ER stress pathway. Journal of Neuroscience and Neurological Disorders, 3, 135-144.

Kardoush, M. I., Ward, B. J., & Ndao, M. (2017). Serum carbonic anhydrase 1 is a biomarker for diagnosis of human schistosoma mansoni infection. The American journal of tropical medicine and hygiene, 96(4), 842.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rat Anti-CA1 Recombinant Antibody (CBXC-1142)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

CA1 Matched Antibody Pair (162) (CAT#: APMAB-162LY)

Related Products

Mouse Anti-CA1 Recombinant Antibody (CBXC-0030) (CAT#: CBMAB-C3244-CQ)

Mouse Anti-CA1 Recombinant Antibody (10E4) (CAT#: CBMAB-C3998-LY)

Mouse Anti-CA1 Recombinant Antibody (CBLC030-LY) (CAT#: CBMAB-C9573-LY)

Rabbit Anti-CA1 Recombinant Antibody (EG441) (CAT#: CBMAB-EN501-LY)

Mouse Anti-CA1 Recombinant Antibody (C7) (CAT#: CBMAB-C0429-CN)

Mouse Anti-CA1 Recombinant Antibody (CBLC029-LY) (CAT#: CBMAB-C9572-LY)

Mouse Anti-CA1 Recombinant Antibody (CBFYC-0681) (CAT#: CBMAB-C0735-FY)

Mouse Anti-CA1 Recombinant Antibody (D4) (CAT#: CBMAB-A1009-LY)

Mouse Anti-CA1 Recombinant Antibody (CBT4277) (CAT#: V2LY-0625-LY2224)

Mouse Anti-CA1 Recombinant Antibody (1E11) (CAT#: CBMAB-C3908-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry