CA1
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Full Name
carbonic anhydrase 1
Function
Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
Biological Process
Bicarbonate transport Source: Reactome
Interleukin-12-mediated signaling pathway Source: Reactome
One-carbon metabolic process Source: GO_Central
Interleukin-12-mediated signaling pathway Source: Reactome
One-carbon metabolic process Source: GO_Central
Cellular Location
Cytoplasm
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Anti-CA1 antibodies
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CompareTarget: CA1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: EG441
Application*: WB, E
Target: CA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: D4
Application*: E, WB, IF, IP
Target: CA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Dog, Pig
Clone: CBLC029-LY
Application*: E, WB, P, IF, IP
Target: CA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Pig
Clone: CBLC030-LY
Application*: E, WB, IF, IP
Target: CA1
Host: Mouse
Antibody Isotype: IgG3, ĸ
Specificity: Mouse, Rat
Clone: C7
Application*: E, WB, IF, IP
Target: CA1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBXC-0030
Application*: E, WB, P, IF, IP
Target: CA1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1142
Application*: WB
Target: CA1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat, Dog, Pig
Clone: CBFYC-0681
Application*: E, WB, P, IF, IP
Target: CA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 10E4
Application*: E, WB
Target: CA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E11
Application*: E, WB
Target: CA1
Sensitivity: 0.016 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: CA1
Sensitivity: 0.024 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Cattle
Assay Type: Sandwich
Reactivity: Cattle
Target: Ca1
Sensitivity: 0.0096 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CA1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 26E3
Application*: E, WB, IH, F
Target: CA1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT247
Application*: WB, E
Target: CA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4277
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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