Mouse Anti-CA1 Recombinant Antibody (CBT4277) (V2LY-0625-LY2224)

Name: Mouse Anti-CA1 Recombinant Antibody (CBT4277)
SKU: V2LY-0625-LY2224
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human

Clone

CBT4277

Antibody Isotype

IgG1

Application

Basic Information

Immunogen

Purified recombinant fragment of CA1 (aa25-90) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Preservative

Sodium azide

Concentration

Batch dependent

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

carbonic anhydrase 1

Entrez Gene ID

759

UniProt ID

P00915

Function

Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.

Biological Process

Bicarbonate transport Source: Reactome
Interleukin-12-mediated signaling pathway Source: Reactome
One-carbon metabolic process Source: GO_Central

Cellular Location

Cytoplasm

More Infomation

References

Feng, Y., Zhong, M., Tang, Y., Liu, X., Liu, Y., Wang, L., & Zhou, H. (2020). The role and underlying mechanism of exosomal CA1 in chemotherapy resistance in diffuse large B cell lymphoma. Molecular Therapy-Nucleic Acids, 21, 452-463.

Yuan, L., Wang, M., Liu, T., Lei, Y., Miao, Q., Li, Q., ... & Chang, X. (2019). Carbonic anhydrase 1-mediated calcification is associated with atherosclerosis, and methazolamide alleviates its pathogenesis. Frontiers in pharmacology, 10, 766.

Lu, D., Peng, X., Jia, X., Li, G., Tan, N., Wei, Z., ... & Liu, J. (2019). Carbonic Anhydrase I modifies SOD1-induced motor neuron toxicity in< em> Drosophila via ER stress pathway. Journal of Neuroscience and Neurological Disorders, 3, 135-144.

Kardoush, M. I., Ward, B. J., & Ndao, M. (2017). Serum carbonic anhydrase 1 is a biomarker for diagnosis of human schistosoma mansoni infection. The American journal of tropical medicine and hygiene, 96(4), 842.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Antibody Pairs

CA1 Matched Antibody Pair (162)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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