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Mouse Anti-CAMK1D Recombinant Antibody (CBYY-C2983) (CBMAB-C4426-YY)

This product is mouse antibody that recognizes CAMK1D. The antibody CBYY-C2983 can be used for immunoassay techniques such as: ELISA, WB, IHC
See all CAMK1D antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2983
Antibody Isotype
IgG2b, κ
Application
ELISA, WB, IHC

Basic Information

Immunogen
CAMK1D (AAH35745, 1 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
calcium/calmodulin-dependent protein kinase ID
Entrez Gene ID
57118
UniProt ID
Q8IU85
Alternative Names
Clathrin Heavy Chain; Clathrin Heavy Chain On Chromosome 17; Clathrin, Heavy Polypeptide-Like 2; Clathrin, Heavy Polypeptide (Hc); CLTCL2; CLH-17; Clathrin, Heavy Chain (Hc); Clathrin Heavy Chain 1;
Function
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Biological Process
Inflammatory response Source: UniProtKB-KW
Negative regulation of apoptotic process Source: Ensembl
Nervous system development Source: UniProtKB-KW
Peptidyl-serine phosphorylation Source: GO_Central
Positive regulation of apoptotic process Source: Ensembl
Positive regulation of CREB transcription factor activity Source: UniProtKB
Positive regulation of neuron projection development Source: UniProtKB
Positive regulation of neutrophil chemotaxis Source: UniProtKB
Positive regulation of phagocytosis Source: UniProtKB
Positive regulation of respiratory burst Source: UniProtKB
Regulation of dendrite development Source: UniProtKB
Regulation of granulocyte chemotaxis Source: UniProtKB
Cellular Location
Nucleus; Cytoplasm. Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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