Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-CAMK1D Recombinant Antibody (CBYY-C2983) (CBMAB-C4426-YY)


See all CAMK1D antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-C2983
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 319-385 mapping at the C-terminus of CaMKIδ of human origin.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA1:100-1:1,000
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
calcium/calmodulin-dependent protein kinase ID
Entrez Gene ID
57118
UniProt ID
Q8IU85
Alternative Names
Clathrin Heavy Chain; Clathrin Heavy Chain On Chromosome 17; Clathrin, Heavy Polypeptide-Like 2; Clathrin, Heavy Polypeptide (Hc); CLTCL2; CLH-17; Clathrin, Heavy Chain (Hc); Clathrin Heavy Chain 1;
Function
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Biological Process
Inflammatory response Source: UniProtKB-KW
Negative regulation of apoptotic process Source: Ensembl
Nervous system development Source: UniProtKB-KW
Peptidyl-serine phosphorylation Source: GO_Central
Positive regulation of apoptotic process Source: Ensembl
Positive regulation of CREB transcription factor activity Source: UniProtKB
Positive regulation of neuron projection development Source: UniProtKB
Positive regulation of neutrophil chemotaxis Source: UniProtKB
Positive regulation of phagocytosis Source: UniProtKB
Positive regulation of respiratory burst Source: UniProtKB
Regulation of dendrite development Source: UniProtKB
Regulation of granulocyte chemotaxis Source: UniProtKB
Cellular Location
Nucleus; Cytoplasm. Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CAMK1D Recombinant Antibody (CBYY-C2983)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry