Human Recombinant CAMK1D protein, GST Tag (V2LY-0526-LY2526)

Name: Human Recombinant CAMK1D protein, GST Tag
SKU: V2LY-0526-LY2526
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant CAMK1D protein, GST Tag consist of Amino Acid: 1-385 and predicts a molecular mass of 69 kDa.

Molecule Mass

69 kDa

Sequence

Amino Acid: 1-385

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>80% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

Tris, NaCl, Glutathione, EDTA, DTT, PMSF, Glycerol

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

calcium/calmodulin-dependent protein kinase ID

Function

Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.

Biological Process

Inflammatory response Source: UniProtKB-KW
Negative regulation of apoptotic process Source: Ensembl
Nervous system development Source: UniProtKB-KW
Peptidyl-serine phosphorylation Source: GO_Central
Positive regulation of apoptotic process Source: Ensembl
Positive regulation of CREB transcription factor activity Source: UniProtKB
Positive regulation of neuron projection development Source: UniProtKB
Positive regulation of neutrophil chemotaxis Source: UniProtKB
Positive regulation of phagocytosis Source: UniProtKB
Positive regulation of respiratory burst Source: UniProtKB
Regulation of dendrite development Source: UniProtKB
Regulation of granulocyte chemotaxis Source: UniProtKB

Cellular Location

Nucleus; Cytoplasm. Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.

Sui, M. H., Zhang, W. W., Geng, D. M., & Sun, D. J. (2021). CircPRKCI regulates proliferation, migration and cycle of lung adenocarcinoma cells by targeting miR-219a-5p-regulated CAMK1D. European Review for Medical and Pharmacological Sciences, 25(4), 1899-1909.

Tong, M. H., Jeeves, M., Rajesh, S., Ludwig, C., Lenoir, M., Kumar, J., ... & Overduin, M. (2020). Backbone resonance assignments of the catalytic and regulatory domains of Ca 2+/calmodulin-dependent protein kinase 1D. Biomolecular NMR Assignments, 14(2), 221-225.

McLennan, S. (2018). Structural & Kinetic Studies of CaMK1D Interactions.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CAMK1D, Active protein, GST Tag (CAT#: V2LY-0526-LY2525)

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Human Recombinant CAMK1D, Active protein, GST Tag (CAT#: V2LY-0526-LY2525)

Mouse Anti-CAMK1D Recombinant Antibody (CBYY-C2983) (CAT#: CBMAB-C4426-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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