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Mouse Anti-CAPNS1 Recombinant Antibody (CBFYC-0803) (CBMAB-C0858-FY)

This product is mouse antibody that recognizes CAPNS1. The antibody CBFYC-0803 can be used for immunoassay techniques such as: WB, IP.
See all CAPNS1 antibodies

Summary

Host Animal
Mouse
Specificity
Cattle, Human
Clone
CBFYC-0803
Antibody Isotype
IgG1
Application
WB, IP

Basic Information

Specificity
Cattle, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
calpain, small subunit 1
Introduction
CAPNS1 (Calpain Small Subunit 1) is a Protein Coding gene. Diseases associated with CAPNS1 include Chronic Neutrophilic Leukemia. Among its related pathways are Apoptosis Modulation and Signaling and Keratinization. Gene Ontology (GO) annotations related to this gene include calcium ion binding and calcium-dependent cysteine-type endopeptidase activity. An important paralog of this gene is CAPNS2.
Entrez Gene ID
Human826
Cattle281664
UniProt ID
HumanP04632
CattleP13135
Alternative Names
Calpain Small Subunit 1; Calcium-Activated Neutral Proteinase Small Subunit; Calcium-Dependent Protease Small Subunit 1; Calpain Regulatory Subunit; CANP Small Subunit; CAPN4; CSS1; CDPS; Calcium-Dependent Protease, Small Subunit
Function
Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Biological Process
Cornification Source: Reactome
Extracellular matrix disassembly Source: Reactome
Positive regulation of cell population proliferation Source: ProtInc
Regulation of macroautophagy Source: ParkinsonsUK-UCL
Cellular Location
Cytoplasm; Cell membrane. Translocates to the plasma membrane upon calcium binding.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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