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Rabbit Anti-CCL23 Recombinant Antibody (007) (CBMAB-C1540-LY)

This product is antibody recognizes CCL23. The antibody 007 immunoassay techniques such as: ELISA.
See all CCL23 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
007
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Recombinant Human CCL23 / MIP 3 Protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-C Motif Chemokine Ligand 23
Introduction
CCL23 (C-C Motif Chemokine Ligand 23) is a Protein Coding gene. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include heparin binding and CCR1 chemokine receptor binding. An important paralog of this gene is CCL15.
Entrez Gene ID
6368
UniProt ID
P55773
Alternative Names
C-C Motif Chemokine Ligand 23; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 23; Myeloid Progenitor Inhibitory Factor 1; Macrophage Inflammatory Protein 3; Chemokine (C-C Motif) Ligand 23; CK-BETA-8; SCYA23; MPIF-1; Ckb-8; MIP-3;
Function
Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
Biological Process
Cell-cell signaling Source: ProtInc
Cellular calcium ion homeostasis Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Negative regulation of C-C chemokine binding Source: UniProtKB
Negative regulation of cell population proliferation Source: ProtInc
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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