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Mouse Anti-CCL26 Recombinant Antibody (CBFYM-0936) (CBMAB-M1085-FY)

This product is mouse antibody that recognizes CCL26. The antibody CBFYM-0936 can be used for immunoassay techniques such as: WB, ICC, IHC-Fr, IHC-P, ELISA.
See all CCL26 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-0936
Antibody Isotype
IgG
Application
WB, ICC, IHC-Fr, IHC-P, ELISA

Basic Information

Immunogen
A mouse monoclonal antibody raised against MIP4a
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-C Motif Chemokine Ligand 26
Introduction
CCL26 is a Protein Coding gene. Diseases associated with CCL26 include Esophagitis and Heart Tumor. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology annotations related to this gene include chemokine activity. An important paralog of this gene is CCL18.
Entrez Gene ID
10344
UniProt ID
Q9Y258
Alternative Names
C-C Motif Chemokine Ligand 26; Macrophage Inflammatory Protein 4-Alpha; Thymic Stroma Chemokine-1; CC Chemokine IMAC; Eotaxin-3; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 26; Chemokine (C-C Motif) Ligand 26; Small Inducible Cytokine A26; Chemokine N1
Function
Chemoattractant for eosinophils and basophils (PubMed:10415065, PubMed:10488147).
Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca2+ mobilization in eosinophils (PubMed:10415065, PubMed:10488147, PubMed:11425309).
Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis (PubMed:20974991).
Biological Process
Cell-cell signaling Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: CAFA
Chemotaxis Source: ProtInc
Eosinophil chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: CAFA
Neutrophil chemotaxis Source: GO_Central
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of chemotaxis Source: CAFA
Positive regulation of endothelial cell proliferation Source: BHF-UCL
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: BHF-UCL
Signal transduction Source: ProtInc
T cell chemotaxis Source: CAFA
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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