Human Anti-CCR8 Recombinant Antibody (2C6) (CBMAB-C3088-LY)

Verhaegen, Y., Liu, L., Nguyen, T. T., Van Loy, T., Voet, A. R., Schols, D., ... & De Jonghe, S. (2021). Palladium-catalyzed cross-coupling reactions on a bromo-naphthalene scaffold in the search for novel human CC chemokine receptor 8 (CCR8) antagonists. Bioorganic Chemistry, 107, 104560.

Fujikawa, M., Koma, Y. I., Hosono, M., Urakawa, N., Tanigawa, K., Shimizu, M., ... & Yokozaki, H. (2021). Chemokine (CC Motif) Ligand 1 Derived from Tumor-Associated Macrophages Contributes to Esophageal Squamous Cell Carcinoma Progression via CCR8-Mediated Akt/Proline-Rich Akt Substrate of 40 kDa/Mammalian Target of Rapamycin Pathway. The American Journal of Pathology, 191(4), 686-703.

Nagai, R., Nagira, M., Nogami, W., Hirata, M., Ueyama, A., Yoshikawa, M., ... & Nagira, Y. (2021). 873 S-531011, a novel anti-human CCR8 antibody: anti-tumor responses through depletion of tumor-infiltrating CCR8-positive Tregs.

Korbecki, J., Grochans, S., Gutowska, I., Barczak, K., & Baranowska-Bosiacka, I. (2020). CC chemokines in a tumor: a review of pro-cancer and anti-cancer properties of receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 ligands. International journal of molecular sciences, 21(20), 7619.

Cadilha, B. L., Dorman, K., Huynh, D., Lorenzini, T., Vänttinen, M., Benmebarek, M. R., ... & Kobold, S. (2020). P06. 03 CC chemokine receptor 8 tumor-directed recruitment enables CAR T cells to reject solid tumors.

Dépis, F., Hu, C., Weaver, J., McGrath, L., Klebanov, B., Buggé, J., ... & Shaffer, D. R. (2020). Preclinical evaluation of JTX-1811, an anti-CCR8 antibody with enhanced ADCC activity, for preferential depletion of tumor-infiltrating regulatory T cells.

Berenguer, J., Lagerweij, T., Zhao, X. W., Dusoswa, S., Van Der Stoop, P., Westerman, B., ... & Wurdinger, T. (2018). Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. Journal of extracellular vesicles, 7(1), 1446660.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols