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CCR8

CCR8 (C-C Motif Chemokine Receptor 8) is a Protein Coding gene. Diseases associated with CCR8 include Molluscum Contagiosum and Kaposi Sarcoma. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR4.
Full Name
C-C Motif Chemokine Receptor 8
Function
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
Biological Process
Calcium-mediated signaling Source: GO_Central
Cell adhesion Source: ProtInc
Cell chemotaxis Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-35
Helical: 36-63
Cytoplasmic: 64-73
Helical: 74-93
Extracellular: 94-107
Helical: 108-129
Cytoplasmic: 130-146
Helical: 147-171
Extracellular: 172-202
Helical: 203-222
Cytoplasmic: 223-238
Helical: 239-263
Extracellular: 264-280
Helical: 281-304
Cytoplasmic: 305-355

Anti-CCR8 antibodies

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Rabbit Anti-CCR8 Recombinant Antibody (1055C) (CBMAB-C9953-LY)

Datasheet SDS
Target: CCR8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 1055C
Application*: F

Rat Anti-CCR8 Recombinant Antibody (SA214G2) (CBMAB-C9955-LY)

Datasheet SDS
Target: CCR8
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: SA214G2
Application*: F

Rat Anti-CCR8 Recombinant Antibody (CBXC-0996) (CBMAB-C1258-CQ)

Datasheet SDS
Target: CCR8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: CBXC-0996
Application*: F

Rabbit Anti-CCR8 Recombinant Antibody (CBXC-0948) (CBMAB-C1210-CQ)

Datasheet SDS
Target: CCR8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXC-0948
Application*: F

Mouse Anti-CCR8 Recombinant Antibody (CBYY-C0224) (CBMAB-C0647-YY)

Datasheet SDS
Target: CCR8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C0224
Application*: F

Rat Anti-CCR8 Recombinant Antibody (CBFYC-0354) (CBMAB-C0393-FY)

Datasheet SDS
Target: CCR8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: CBFYC-0354
Application*: F

Rabbit Anti-CCR8 Recombinant Antibody (CBFYC-0154) (CBMAB-C0176-FY)

Datasheet SDS
Target: CCR8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-0154
Application*: F

Rat Anti-CCR8 Recombinant Antibody (14L136) (CBMAB-C3088-LY)

Datasheet SDS
Target: CCR8
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L136
Application*: F

Rat Anti-CCR8 Recombinant Antibody (191704) (CBMAB-C0454-LY)

Datasheet SDS
Target: CCR8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: 191704
Application*: N
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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