CCR8

CCR8 (C-C Motif Chemokine Receptor 8) is a Protein Coding gene. Diseases associated with CCR8 include Molluscum Contagiosum and Kaposi Sarcoma. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR4.
Full Name
C-C Motif Chemokine Receptor 8
Function
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
Biological Process
Calcium-mediated signaling Source: GO_Central
Cell adhesion Source: ProtInc
Cell chemotaxis Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-35
Helical: 36-63
Cytoplasmic: 64-73
Helical: 74-93
Extracellular: 94-107
Helical: 108-129
Cytoplasmic: 130-146
Helical: 147-171
Extracellular: 172-202
Helical: 203-222
Cytoplasmic: 223-238
Helical: 239-263
Extracellular: 264-280
Helical: 281-304
Cytoplasmic: 305-355
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Anti-CCR8 antibodies

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Rat Anti-CCR8 Recombinant Antibody (CBXC-0996) (CBMAB-C1258-CQ)

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Target: CCR8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-0996
Application*: F, B
Functional Assay
Datasheet SDS

Mouse Anti-CCR8 Recombinant Antibody (CBYY-C0224) (CBMAB-C0647-YY)

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Target: CCR8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C0224
Application*: F
Datasheet SDS

Rabbit Anti-CCR8 Recombinant Antibody (CBXC-0948) (CBMAB-C1210-CQ)

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Target: CCR8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXC-0948
Application*: F
Datasheet SDS

Human Anti-CCR8 Recombinant Antibody (CBFYC-0354) (CBMAB-C0393-FY)

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Target: CCR8
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0354
Application*: F, E
Datasheet SDS

Rabbit Anti-CCR8 Recombinant Antibody (CBFYC-0154) (CBMAB-C0176-FY)

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Target: CCR8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYC-0154
Application*: WB, IF, IC
Datasheet SDS

Human Anti-CCR8 Recombinant Antibody (2C6) (CBMAB-C3088-LY)

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Target: CCR8
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C6
Application*: F
Datasheet SDS

Human Anti-CCR8 Recombinant Antibody (2C10) (CBMAB-C0454-LY)

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Target: CCR8
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C10
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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