Armenian Hamster Anti-CD209b Recombinant Antibody (AG12) (V2LY-0524-LY87)

Name: Armenian Hamster Anti-CD209b Recombinant Antibody (AG12)
SKU: V2LY-0524-LY87
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Armenian Hamster

Clone

AG12

Application

Blocking, FC, IHC-F, WB

Immunogen

Purified Recombinant Mouse CD209b (C-terminal peptide)

Host Species

Armenian Hamster

Specificity

Mouse

Antibody Isotype

IgG1, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Endotoxin

< 1.0 EU/mg as determined by the LAL method

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

5 mg/ml

Purity

>95% by SDS Page

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

CD209b antigen

Entrez Gene ID

69165

UniProt ID

Q8CJ91

Alternative Names

1810030I22Rik; DC-SIGNR1; OtB7; SIGNR1; mSIGNR1

Function

Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

Biological Process

Detection of bacterium Source: MGI
Detection of yeast Source: MGI
Endocytosis Source: MGI
Phagocytosis, recognition Source: MGI
Positive regulation of phagocytosis Source: MGI
Positive regulation of tumor necrosis factor production Source: MGI

Cellular Location

Membrane

Topology

Cytoplasmic: 1-52
Helical: 53-73
Extracellular: 74-325

Yang, K., He, Y., Park, C. G., Kang, Y. S., Zhang, P., Han, Y., ... & Chen, T. (2019). Yersinia pestis interacts with SIGNR1 (CD209b) for promoting host dissemination and infection. Frontiers in immunology, 10, 96.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Recombinant CD209B protein, His Tag (CAT#: V2LY-0526-LY8910)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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