Mouse Recombinant CD209B protein, His Tag (V2LY-0526-LY8910)

Name: Mouse Recombinant CD209B protein, His Tag
SKU: V2LY-0526-LY8910
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

His Tag

Protein Construction

This product is Mouse Recombinant CD209B protein, His Tag consist of Amino Acid: 74-325 and predicts a molecular mass of 31.4 kDa.

Molecule Mass

31.4 kDa

Verified

HPLC

Sequence

Amino Acid: 74-325

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥95% as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

CD209b antigen

Alternative Names

1810030I22Rik; DC-SIGNR1; OtB7; SIGNR1; mSIGNR1

Function

Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

Biological Process

Detection of bacterium Source: MGI
Detection of yeast Source: MGI
Endocytosis Source: MGI
Phagocytosis, recognition Source: MGI
Positive regulation of phagocytosis Source: MGI
Positive regulation of tumor necrosis factor production Source: MGI

Cellular Location

Membrane

Topology

Cytoplasmic: 1-52
Helical: 53-73
Extracellular: 74-325

Yang, K., He, Y., Park, C. G., Kang, Y. S., Zhang, P., Han, Y., ... & Chen, T. (2019). Yersinia pestis interacts with SIGNR1 (CD209b) for promoting host dissemination and infection. Frontiers in immunology, 10, 96.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Armenian Hamster Anti-CD209b Recombinant Antibody (AG12) (CAT#: V2LY-0524-LY87)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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