Rabbit Anti-CD302 Recombinant Antibody (071) (CBMAB-C1848-LY)

This product is antibody recognizes CD302. The antibody 071 immunoassay techniques such as: ELISA, IHC-P.
See all CD302 antibodies

Summary

Host Animal

Rabbit

Specificity

Mouse

Clone

071

Antibody Isotype

IgG

Application

ELISA, IHC-P

Basic Information

Immunogen

Recombinant Mouse CD302 / CLEC13A protein

Specificity

Mouse

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

CD302 Molecule

Introduction

CD302 (CD302 Molecule) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include carbohydrate binding.

Entrez Gene ID

66205

UniProt ID

Q9DCG2

Function

Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.

Biological Process

Phagocytosis Source: MGI

Cellular Location

Membrane; Filopodium; Cell cortex; Microvillus. Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface.

Topology

Extracellular: 23-168
Helical: 169-189
Cytoplasmic: 190-232

PTM

May be heterogeneously N-glycosylated in some cell types.

References

Brown, R. J., Tegtmeyer, B., Sheldon, J., Khera, T., Anggakusuma, Todt, D., ... & Pietschmann, T. (2020). Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Science advances, 6(45), eabd3233.

Kok, C. H., Liu, L., Yeung, D. T., Saunders, V. A., Dang, P., & Hughes, T. P. (2019). A Combination of CD302 gene Expression and 3-Months BCR-ABL1 Level Predicts Inferior Achievement of Deep Molecular Response in CP-CML Patients Treated with Imatinib.

Lo, T. H., Abadir, E., Gasiorowski, R. E., Kabani, K., Ramesh, M., Orellana, D., ... & Clark, G. J. (2019). Examination of CD302 as a potential therapeutic target for acute myeloid leukemia. Plos one, 14(5), e0216368.

Alaterre, E., Raimbault, S., Goldschmidt, H., Bouhya, S., Requirand, G., Robert, N., ... & Moreaux, J. (2017). CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma. Oncotarget, 8(58), 98931.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

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Mouse Anti-CD302 Recombinant Antibody (771910)

Rabbit Anti-CD302 Recombinant Antibody (CBFYC-1216)

Rabbit Anti-CD302 Recombinant Antibody (EG538)

Human Anti-CD302 Recombinant Antibody (CBXC-0868)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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