Mouse Anti-CD302 Recombinant Antibody (CBT3819) (V2LY-0625-LY1147)

Name: Mouse Anti-CD302 Recombinant Antibody (CBT3819)
SKU: V2LY-0625-LY1147
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human

Clone

CBT3819

Antibody Isotype

IgG1

Application

Basic Information

Immunogen

Purified recombinant fragment of human CD302 (AA: extra 23-168) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

CD302 molecule

Entrez Gene ID

9936

UniProt ID

Q8IX05

Function

Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.

Biological Process

Phagocytosis

Cellular Location

Membrane
Cell projection, filopodium
Cytoplasm, cell cortex
Cell projection, microvillus

Topology

Extracellular: 23-168
Helical: 169-189
Cytoplasmic: 190-232

PTM

May be heterogeneously N-glycosylated in some cell types.

More Infomation

References

Brown, R. J., Tegtmeyer, B., Sheldon, J., Khera, T., Anggakusuma, Todt, D., ... & Pietschmann, T. (2020). Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Science advances, 6(45), eabd3233.

Kok, C. H., Liu, L., Yeung, D. T., Saunders, V. A., Dang, P., & Hughes, T. P. (2019). A Combination of CD302 gene Expression and 3-Months BCR-ABL1 Level Predicts Inferior Achievement of Deep Molecular Response in CP-CML Patients Treated with Imatinib.

Lo, T. H., Abadir, E., Gasiorowski, R. E., Kabani, K., Ramesh, M., Orellana, D., ... & Clark, G. J. (2019). Examination of CD302 as a potential therapeutic target for acute myeloid leukemia. Plos one, 14(5), e0216368.

Alaterre, E., Raimbault, S., Goldschmidt, H., Bouhya, S., Requirand, G., Robert, N., ... & Moreaux, J. (2017). CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma. Oncotarget, 8(58), 98931.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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