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Mouse Anti-CD53 Recombinant Antibody (63-5A3) (CBMAB-C7899-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
63-5A3
Antibody Isotype
IgG2b, κ
Application
FC, IF

Basic Information

Immunogen
Human Sezary cells.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
FC1-2 μg/10^6 cells
IF(ICC)1-2 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.01% BSA
Preservative
0.05% sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CD53 Molecule
Introduction
CD53 (CD53 Molecule) is a Protein Coding gene. Diseases associated with CD53 include Intestinal Tuberculosis and Gastrointestinal Tuberculosis. Among its related pathways are Innate Immune System.

An important paralog of this gene is TSPAN9.
Entrez Gene ID
963
UniProt ID
P19397
Function
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).
Biological Process
Neutrophil degranulation Source: Reactome
Positive regulation of myoblast fusion Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Cell membrane; Cell junction; Membrane. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.
Topology
Cytoplasmic: 1-11
Helical: 12-32
Extracellular: 33-54
Helical: 55-69
Cytoplasmic: 70-80
Helical: 81-106
Extracellular: 107-181
Helical: 182-206
Cytoplasmic: 207-219
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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