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CD53

CD53 (CD53 Molecule) is a Protein Coding gene. Diseases associated with CD53 include Intestinal Tuberculosis and Gastrointestinal Tuberculosis. Among its related pathways are Innate Immune System. An important paralog of this gene is TSPAN9.
Full Name
CD53 Molecule
Function
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).
Biological Process
Neutrophil degranulation Source: Reactome
Positive regulation of myoblast fusion Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Cell membrane; Cell junction; Membrane. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.
Topology
Cytoplasmic: 1-11
Helical: 12-32
Extracellular: 33-54
Helical: 55-69
Cytoplasmic: 70-80
Helical: 81-106
Extracellular: 107-181
Helical: 182-206
Cytoplasmic: 207-219

Anti-CD53 antibodies

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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
Target: CD53
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat, Mouse
Clone: OX-44
Application*: F, IP, IF, P
Target: CD53
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-2972
Application*: F, IF
Target: CD53
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1499
Application*: F, WB, IF, IH
Target: CD53
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0742
Application*: F
Target: CD53
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0132
Application*: IP, IF, F
Target: CD53
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-0320
Application*: IF, P, IP, WB, E
Target: CD53
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 13
Application*: E
Target: CD53
Host: Rabbit
Antibody Isotype: IgG
Specificity: Monkey
Clone: 104
Application*: E, WB, IP
Target: CD53
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 004
Application*: WB, IP
Target: CD53
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 63-5A3
Application*: F, IF
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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