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Mouse Anti-CER1 Recombinant Antibody (CBYY-C1884) (CBMAB-C3322-YY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1884
Antibody Isotype
IgG1
Application
ELISA, WB, IHC, IF

Basic Information

Immunogen
Purified recombinant fragment of human Cerberus expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
ELISA1:10,000
WB1:500-1:2,000
IF(ICC)1:50-1:200
IHC1:200-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.5% BSA, 50% Glycerol
Preservative
0.03% sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cerberus 1, DAN Family BMP Antagonist
Entrez Gene ID
9350
UniProt ID
O95813
Alternative Names
Complement Factor I; Konglutinogen-Activating Factor; C3B/C4B Inactivator; C3b-Inactivator; IF; Complement Control Protein Factor I; Complement Factor I Heavy Chain; Light Chain Of Factor I; Complement Component I; I Factor (Complement);
Function
Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity).
Biological Process
Anterior/posterior axis specification Source: BHF-UCL
Anterior/posterior pattern specification Source: BHF-UCL
Bone mineralization Source: BHF-UCL
Cell migration involved in gastrulation Source: BHF-UCL
Cellular response to BMP stimulus Source: BHF-UCL
Cellular response to cadmium ion Source: Ensembl
Determination of dorsal identity Source: BHF-UCL
Determination of heart left/right asymmetry Source: GO_Central
Gastrulation Source: BHF-UCL
Growth plate cartilage chondrocyte proliferation Source: BHF-UCL
Negative regulation of activin receptor signaling pathway Source: BHF-UCL
Negative regulation of BMP signaling pathway Source: BHF-UCL
Negative regulation of cell population proliferation Source: BHF-UCL
Negative regulation of mesoderm development Source: BHF-UCL
Negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Source: GO_Central
Nervous system development Source: BHF-UCL
Sequestering of BMP from receptor via BMP binding Source: Reactome
Sequestering of BMP in extracellular matrix Source: BHF-UCL
Signal transduction involved in regulation of gene expression Source: BHF-UCL
Ureteric bud development Source: UniProtKB
Cellular Location
Secreted
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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