CER1

This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]
Full Name
Cerberus 1, DAN Family BMP Antagonist
Function
Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity).
Biological Process
Anterior/posterior axis specification Source: BHF-UCL
Anterior/posterior pattern specification Source: BHF-UCL
Bone mineralization Source: BHF-UCL
Cell migration involved in gastrulation Source: BHF-UCL
Cellular response to BMP stimulus Source: BHF-UCL
Cellular response to cadmium ion Source: Ensembl
Determination of dorsal identity Source: BHF-UCL
Determination of heart left/right asymmetry Source: GO_Central
Gastrulation Source: BHF-UCL
Growth plate cartilage chondrocyte proliferation Source: BHF-UCL
Negative regulation of activin receptor signaling pathway Source: BHF-UCL
Negative regulation of BMP signaling pathway Source: BHF-UCL
Negative regulation of cell population proliferation Source: BHF-UCL
Negative regulation of mesoderm development Source: BHF-UCL
Negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Source: GO_Central
Nervous system development Source: BHF-UCL
Sequestering of BMP from receptor via BMP binding Source: Reactome
Sequestering of BMP in extracellular matrix Source: BHF-UCL
Signal transduction involved in regulation of gene expression Source: BHF-UCL
Ureteric bud development Source: UniProtKB
Cellular Location
Secreted
PTM
N-glycosylated.
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Anti-CER1 antibodies

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Rabbit Anti-CER1 Recombinant Antibody (CBFYC-1730) (CBMAB-C1792-FY)

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Target: CER1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1730
Application*: E
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBT335) (V2LY-0625-LY3588)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT335
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBT336) (V2LY-0625-LY3587)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT336
Application*: WB, E
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBT4392) (V2LY-0625-LY2382)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4392
Application*: IH
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBT4730) (V2LY-0625-LY2381)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4730
Application*: WB
Datasheet SDS

CER1 Matched Antibody Pair (263) (APMAB-263LY)

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Target: CER1
Specificity: Human
Datasheet SDS

CER1 Matched Antibody Pair (262) (APMAB-262LY)

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Target: CER1
Specificity: Human
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBXC-0982) (CBMAB-C1244-CQ)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXC-0982
Application*: WB, P
Datasheet SDS

Rat Anti-CER1 Recombinant Antibody (CBYY-C1885) (CBMAB-C3323-YY)

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Target: CER1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-C1885
Application*: WB
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBYY-C1884) (CBMAB-C3322-YY)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1884
Application*: E, WB, IH, IF
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBYY-C1883) (CBMAB-C3321-YY)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1883
Application*: IH, WB
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (CBFYC-1729) (CBMAB-C1791-FY)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1729
Application*: WB, IP, IF, E
Datasheet SDS

Rat Anti-CER1 Recombinant Antibody (CBFYC-1727) (CBMAB-C1789-FY)

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Target: CER1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBFYC-1727
Application*: IH, WB
Datasheet SDS

Mouse Anti-CER1 Recombinant Antibody (5C6) (CBMAB-C7402-LY)

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Target: CER1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C6
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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