Mouse Anti-CLDN5 Recombinant Antibody (CBCNC-011) (CBMAB-C0904-CN)

Yang, Z., Lin, P., Chen, B., Zhang, X., Xiao, W., Wu, S., ... & Zhang, J. (2021). Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5). Autophagy, 17(10), 3048-3067.

Chiba, H., Ichikawa‐Tomikawa, N., Imura, T., & Sugimoto, K. (2021). The region‐selective regulation of endothelial claudin‐5 expression and signaling in brain health and disorders. Journal of Cellular Physiology.

Tachibana, K., Hashimoto, Y., Shirakura, K., Okada, Y., Hirayama, R., Iwashita, Y., ... & Kondoh, M. (2021). Safety and efficacy of an anti-claudin-5 monoclonal antibody to increase blood–brain barrier permeability for drug delivery to the brain in a non-human primate. Journal of Controlled Release.

Berndt, P., Winkler, L., Cording, J., Breitkreuz-Korff, O., Rex, A., Dithmer, S., ... & Haseloff, R. F. (2019). Tight junction proteins at the blood–brain barrier: far more than claudin-5. Cellular and molecular life sciences, 76(10), 1987-2002.

Hashimoto, Y., Zhou, W., Hamauchi, K., Shirakura, K., Doi, T., Yagi, K., ... & Takeda, H. (2018). Engineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5. Scientific reports, 8(1), 1-12.

Zhang, X., Chen, J., Sun, L., & Xu, Y. (2018). SIRT1 deacetylates KLF4 to activate Claudin‐5 transcription in ovarian cancer cells. Journal of cellular biochemistry, 119(2), 2418-2426.

Neuhaus, W., Piontek, A., Protze, J., Eichner, M., Mahringer, A., Subileau, E. A., ... & Piontek, J. (2018). Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain. Biomaterials, 161, 129-143.

Hashimoto, Y., Shirakura, K., Okada, Y., Takeda, H., Endo, K., Tamura, M., ... & Kondoh, M. (2017). Claudin-5-binders enhance permeation of solutes across the blood-brain barrier in a mammalian model. Journal of Pharmacology and Experimental Therapeutics, 363(2), 275-283.

Ma, S. C., Li, Q., Peng, J. Y., Zhouwen, J. L., Diao, J. F., Niu, J. X., ... & Jiang, W. G. (2017). Claudin‐5 regulates blood‐brain barrier permeability by modifying brain microvascular endothelial cell proliferation, migration, and adhesion to prevent lung cancer metastasis. CNS neuroscience & therapeutics, 23(12), 947-960.

Nishiura, K., Ichikawa-Tomikawa, N., Sugimoto, K., Kunii, Y., Kashiwagi, K., Tanaka, M., ... & Chiba, H. (2017). PKA activation and endothelial claudin-5 breakdown in the schizophrenic prefrontal cortex. Oncotarget, 8(55), 93382.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols