Mouse Anti-CMPK1 Recombinant Antibody (CBFYC-1973) (V2LY-1206-LY369)

Name: Mouse Anti-CMPK1 Recombinant Antibody (CBFYC-1973)
SKU: V2LY-1206-LY369
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYC-1973

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 92-196 mapping at the C-terminal of CMPK of human.

Host Species

Mouse

Specificity

Human, Mouse, Rat, Pig, Dog

Antibody Isotype

IgG1, κ

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

0.1% gelatin

Preservative

<0.1% sodium azide

Concentration

0.2 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

cytidine/uridine monophosphate kinase 1

Entrez Gene ID

Human	51727
Mouse	66588

UniProt ID

Human	P30085
Mouse	Q9DBP5

Function

Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.

Biological Process

de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
CDP biosynthetic process Source: GO_Central
Nucleobase-containing small molecule interconversion Source: Reactome
Nucleoside diphosphate phosphorylation Source: UniProtKB
Nucleoside triphosphate biosynthetic process Source: UniProtKB
Pyrimidine ribonucleotide biosynthetic process Source: ProtInc
UDP biosynthetic process Source: GO_Central

Cellular Location

Nucleus; Cytoplasm. Predominantly cytoplasmic, less than 15% nuclear.

Li, W., Wang, Q., Feng, Q., Wang, F., Yan, Q., Gao, S. J., & Lu, C. (2019). Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network. PLoS pathogens, 15(1), e1007578.

Zhao, Y., Yu, Y., & Ye, L. (2019). MiR-3613-3p impairs IFN-induced immune response by targeting CMPK1 in chronic hepatitis B. Infection, Genetics and Evolution, 74, 103919.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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