Human Recombinant CMPK1 protein, His Tag (V2LY-0526-LY7543)

Name: Human Recombinant CMPK1 protein, His Tag
SKU: V2LY-0526-LY7543
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant CMPK1 protein, His Tag consist of Amino Acid: 1-196 and predicts a molecular mass of 24.5 kDa.

Molecule Mass

24.5 kDa

Sequence

Amino Acid: 1-196

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>95% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

cytidine/uridine monophosphate kinase 1

Function

Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.

Biological Process

de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
CDP biosynthetic process Source: GO_Central
Nucleobase-containing small molecule interconversion Source: Reactome
Nucleoside diphosphate phosphorylation Source: UniProtKB
Nucleoside triphosphate biosynthetic process Source: UniProtKB
Pyrimidine ribonucleotide biosynthetic process Source: ProtInc
UDP biosynthetic process Source: GO_Central

Cellular Location

Nucleus; Cytoplasm. Predominantly cytoplasmic, less than 15% nuclear.

Li, W., Wang, Q., Feng, Q., Wang, F., Yan, Q., Gao, S. J., & Lu, C. (2019). Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network. PLoS pathogens, 15(1), e1007578.

Zhao, Y., Yu, Y., & Ye, L. (2019). MiR-3613-3p impairs IFN-induced immune response by targeting CMPK1 in chronic hepatitis B. Infection, Genetics and Evolution, 74, 103919.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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