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Mouse Anti-DAP Recombinant Antibody (3C5) (V2LY-0125-LY1084)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3C5
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
DAP (1-102aa) full-length recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Death Associated Protein
Entrez Gene ID
1611
UniProt ID
P51397
Function
Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Apoptotic process Source: MGI
Apoptotic signaling pathway Source: UniProtKB
Autophagy Source: UniProtKB-KW
Cellular response to amino acid starvation Source: UniProtKB
Negative regulation of autophagy Source: UniProtKB
Negative regulation of NF-kappaB transcription factor activity Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
PTM
Phosphorylated. Phosphorylation by MTOR inhibits the suppressive activity of DAP toward autophagy.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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