Mouse Anti-DEFB4B Recombinant Antibody (14D56) (CBMAB-D0690-YC)

Name: Mouse Anti-DEFB4B Recombinant Antibody (14D56)
SKU: CBMAB-D0690-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

14D56

Application

ELISA

Immunogen

Synthetic peptide corresponding to a.a.4-41 from human Defensin-2

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Defensin Beta 4B

Introduction

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. DEFB4B is an antibiotic peptide which is locally regulated by inflammation.

Entrez Gene ID

100289462

UniProt ID

O15263

Alternative Names

Defensin Beta 4B; Defensin, Beta 4, Pseudogene; Beta Defensin 2; Beta-Defensin 2; Skin-Antimicrobial Peptide 1; Defensin, Beta 4B; Defensin, Beta 2; Beta-Defensin 4B; Beta Defensin-2;

Function

Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036).

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Antimicrobial humoral response Source: Reactome
Cell chemotaxis Source: GO_Central
Chemotaxis Source: UniProtKB
Defense response to bacterium Source: MGI
Defense response to Gram-negative bacterium Source: UniProtKB
Defense response to Gram-positive bacterium Source: UniProtKB
G protein-coupled receptor signaling pathway Source: ProtInc
Immune response Source: ProtInc
Killing of cells of other organism Source: UniProtKB

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-DEFB4B Recombinant Antibody (14D56) (CAT#: V2LY-0425-LY162)

Related Products

Mouse Anti-DEFB4B Recombinant Antibody (D0691) (CAT#: V2LY-0425-LY163)

Mouse Anti-DEFB4B Recombinant Antibody (14D56) (CAT#: V2LY-0425-LY162)

Mouse Anti-DEFB4B Recombinant Antibody (L12-4C-C2) (CAT#: CBMAB-D0691-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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