Mouse Anti-DFFB Recombinant Antibody (CBYCD-246) (V2LY-0425-LY222)

Name: Mouse Anti-DFFB Recombinant Antibody (CBYCD-246)
SKU: V2LY-0425-LY222
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYCD-246

Antibody Isotype

IgG1

Application

WB, IF

Basic Information

Immunogen

E. coli-derived recombinant human DFF40/CAD (Met1-Gln338).

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	0.5 μg/ml
IF(ICC)	8-25 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

Trehalose & PBS

Preservative

None

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

DNA Fragmentation Factor Subunit Beta

Entrez Gene ID

1677

UniProt ID

O76075

Function

Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.

Biological Process

Apoptotic chromosome condensation Source: UniProtKB
Apoptotic DNA fragmentation Source: CAFA
DNA catabolic process Source: CAFA

Cellular Location

Nucleus; Cytoplasm

More Infomation

References

Han, D. S., Ni, M., Chan, R. W., Chan, V. W., Lui, K. O., Chiu, R. W., & Lo, Y. D. (2020). The biology of cell-free DNA fragmentation and the roles of DNASE1, DNASE1L3, and DFFB. The American Journal of Human Genetics, 106(2), 202-214.

Gao, Y., Zhang, X., Wang, T., Zhang, Y., Wang, Q., & Hu, Y. (2020). HNRNPCL1, PRAMEF1, CFAP74, and DFFB: Common Potential Biomarkers for Sporadic and Suspected Lynch Syndrome Endometrial Cancer. Cancer management and research, 12, 11231.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

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Mouse Anti-DFFB Recombinant Antibody (CBYCD-248)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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